刘林川

2021年07月07日 16:51  点击:[]

刘林川,首聘教授,博士,博/硕士生导师

邮箱:lcliu@scau.edu.cn

研究方向: 植物细胞蛋白质稳态调控机制


个人简介:

2013年毕业于中国科学院遗传与发育生物学研究所,获遗传学博士学位;2013年至2018年就职于中国科学院上海生命科学研究院植物逆境生物学研究中心,任助理研究员、副研究员。2018年起任华南农业大学林学与风景园林学院首聘教授。现任国家自然科学基金和广东省自然科学基金评审专家,《植物生理学报》编委。

 

科研成果:

近年来,以模式植物水稻和拟南芥为材料,围绕植物激素信号传导和植物生长发育调控,在生长素运输、油菜素内酯信号转导和蛋白质质量控制领域开展了深入系统的研究工作。研究成果发表在PNAS, Nature Communications, Plant Cell, Plant Physiology等杂志。现主持国家自然科学基金2项,参加国家自然科学基金重点项目、中国科学院战略性先导专项等项目4项,获得授权的国内和国际发明专利3项,参编论著和专业教材3部。


科研项目:

1. 国家自然科学基金面上项目,植物ABCB1的质量控制及其协同油菜素内酯信号和生长素运输的分子机制,2020/01-2023/12,58万元,主持,在研

2. 国家自然科学基金青年项目,核苷酸单糖转运蛋白ROCK1/EBS8在拟南芥内质网蛋白质质量控制中的作用机制研究,2017/01-2019/12, 21万元,主持,已结题

3. 国家自然科学基金重点项目,植物内质网介导的蛋白质降解机制2018/01-2022/12,278万元,参加(排名第2),在研


代表性论文:

  1. Lin L, Zhang C, Chen Y, Wang Y, Wang D, Liu X, Wang M, Mao J, Zhang J, Xing W, Liu L*, Li J* (2019) PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex. Nature Communications 10: 3492 (Co-corresponding author)

  2. Liu L, Li J (2019) Communications Between the Endoplasmic Reticulum and Other Organelles During Abiotic Stress Response in Plants. Fronter in Plant Science 10: 749

  3. Xiao Y, Liu D, Zhang G, Gao S, Liu L, Xu F, Che R, Wang Y, Tong H, Chu C (2019) Big Grain3, encoding a purine permease, regulates grain size via modulating cytokinin transport in rice. Journal of Integrative Plant Biology 61: 581-597

  4. Hu B, Jiang Z, Wang W, Qiu Y, Zhang Z, Liu Y, Li A, Gao X, Liu L, Qian Y, Huang X, Yu F, Kang S, Wang Y, Xie J, Cao S, Zhang L, Wang Y, Xie Q, Kopriva S, Chu C (2019) Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants. Nature Plants 5: 401-413

  5. Zhang X, Zhou L, Qin Y, Chen Y, Liu X, Wang M, Mao J, Zhang J, He Z, Liu L*, Li J* (2018) A Temperature-Sensitive Misfolded bri1-301 Receptor Requires Its Kinase Activity to Promote Growth. Plant Physiology 178: 1704-1719 (Co-corresponding author)

  6. Liu L, Tong H, Xiao Y, Che R, Xu F, Hu B, Liang C, Chu J, Li J, Chu C (2015) Activation of Big Grain1 significantly improves grain size by regulating auxin transport in rice. Proc Natl Acad Sci U S A 112: 11102-11107

  7. Liu Y, Zhang C, Wang D, Su W, Liu L, Wang M, Li J (2015) EBS7 is a plant-specific component of a highly conserved endoplasmic reticulum-associated degradation system in Arabidopsis. Proc Natl Acad Sci U S A 112: 12205-12210

  8. Hu B, Wang W, Ou S, Tang J, Li H, Che R, Zhang Z, Chai X, Wang H, Wang Y, Liang C, Liu L, Piao Z, Deng Q, Deng K, Xu C, Liang Y, Zhang L, Li L, Chu C (2015) Variation in NRT1.1B contributes to nitrate-use divergence between rice subspecies. Nature Genetics 47: 834-838

  9. Che R, Tong H, Shi B, Liu Y, Fang S, Liu D, Xiao Y, Hu B, Liu L, Wang H, Zhao M, Chu C (2015) Control of grain size and rice yield by GL2-mediated brassinosteroid responses. Nature Plants 2: 15195

  10. Tong H, Xiao Y, Liu D, Gao S, Liu L, Yin Y, Jin Y, Qian Q, Chu C (2014) Brassinosteroid regulates cell elongation by modulating gibberellin metabolism in rice. Plant Cell 26: 4376-4393

  11. Liu C, Mao B, Ou S, Wang W, Liu L, Wu Y, Chu C, Wang X (2014) OsbZIP71, a bZIP transcription factor, confers salinity and drought tolerance in rice. Plant Molecular Biology 84: 19-36

  12. Liang C, Wang Y, Zhu Y, Tang J, Hu B, Liu L, Ou S, Wu H, Sun X, Chu J, Chu C (2014) OsNAP connects abscisic acid and leaf senescence by fine-tuning abscisic acid biosynthesis and directly targeting senescence-associated genes in rice. Proc Natl Acad Sci U S A 111: 10013-10018

  13. Tong H, Liu L, Jin Y, Du L, Yin Y, Qian Q, Zhu L, Chu C (2012) DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice. Plant Cell 24: 2562-2577

  14. Sun C, Fang J, Zhao T, Xu B, Zhang F, Liu L, Tang J, Zhang G, Deng X, Chen F, Qian Q, Cao X, Chu C (2012) The histone methyltransferase SDG724 mediates H3K36me2/3 deposition at MADS50 and RFT1 and promotes flowering in rice. Plant Cell 24: 3235-3247

  15. Lin A, Wang Y, Tang J, Xue P, Li C, Liu L, Hu B, Yang F, Loake GJ, Chu C (2012) Nitric oxide and protein S-nitrosylation are integral to hydrogen peroxide-induced leaf cell death in rice. Plant Physiology158: 451-464

  16. Tang J, Zhu X, Wang Y, Liu L, Xu B, Li F, Fang J, Chu C (2011) Semi-dominant mutations in the CC-NB-LRR-type R gene, NLS1, lead to constitutive activation of defense responses in rice. Plant Journal 66: 996-1007

  17. Sun C, Liu L, Tang J, Lin A, Zhang F, Fang J, Zhang G, Chu C (2011) RLIN1, encoding a putative coproporphyrinogen III oxidase, is involved in lesion initiation in rice. Journal of Genetics and Genomics 38: 29-37 (Co-first author)

  18. Li C, Wang Y, Liu L, Hu Y, Zhang F, Mergen S, Wang G, Schlappi MR, Chu C (2011) A rice plastidial nucleotide sugar epimerase is involved in galactolipid biosynthesis and improves photosynthetic efficiency. PLoS Genetics 7: e1002196

  19. Hu B, Zhu C, Li F, Tang J, Wang Y, Lin A, Liu L, Che R, Chu C (2011) LEAF TIP NECROSIS1 plays a pivotal role in the regulation of multiple phosphate starvation responses in rice. Plant Physiology 156: 1101-1115

 



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